Recombinant human erythropoietin reduces rhabdomyolysis-induced acute renal failure in rats.

@article{Yang2012RecombinantHE,
  title={Recombinant human erythropoietin reduces rhabdomyolysis-induced acute renal failure in rats.},
  author={Fwu-Lin Yang and Yi-Maun Subeq and Yi-Han Chiu and R J Lee and Chung-Jen Lee and Bang-Gee Hsu},
  journal={Injury},
  year={2012},
  volume={43 3},
  pages={367-73}
}
BACKGROUND Rhabdomyolysis is one of the causes of acute renal failure. Erythropoietin (EPO) has been found to interact with its receptor (EPO-R) expressed in a large variety of non-haematopoietic tissues to induce a range of pleiotropic cytoprotective actions. In this study, we used recombinant human erythropoietin (rhEPO) to study the effects on the glycerol-induced rhabdomyolysis with acute renal failure in rats. METHODS Twenty-four rats were divided into three groups as glycerol group… CONTINUE READING

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