Recombinant human Hsp70 protects against lipoteichoic acid-induced inflammation manifestations at the cellular and organismal levels

@article{Vinokurov2011RecombinantHH,
  title={Recombinant human Hsp70 protects against lipoteichoic acid-induced inflammation manifestations at the cellular and organismal levels},
  author={Maxim G Vinokurov and Vladimir Ostrov and Marina Yurinskaya and David G. Garbuz and Arkady N. Murashev and Olga A. Antonova and Mikhail Evgen’ev},
  journal={Cell Stress and Chaperones},
  year={2011},
  volume={17},
  pages={89-101}
}
It has been previously reported that pretreatment with exogenous heat shock protein 70 (Hsp70) is able to protect cells and animals from the deleterious effects of bacterial lipopolysaccharide (LPS) produced by Gram-negative bacteria. However, the effects of Hsp70 pretreatment on lipoteichoic acid (LTA) challenge resulted from Gram-positive bacteria infection have not been fully elucidated. In this study, we demonstrated that preconditioning with human recombinant Hsp70 ameliorates various… CONTINUE READING