Recombinant expression of rt-PA gene (encoding Reteplase) in gametophytes of the seaweed Laminaria japonica (Laminariales, Phaeophyta)

@article{Zhang2008RecombinantEO,
  title={Recombinant expression of rt-PA gene (encoding Reteplase) in gametophytes of the seaweed Laminaria japonica (Laminariales, Phaeophyta)},
  author={Yichen Zhang and Peng Jiang and Jiangtao Gao and Jianmin Liao and Shijing Sun and Zilong Shen and Song Qin},
  journal={Science in China Series C: Life Sciences},
  year={2008},
  volume={51},
  pages={1116-1120}
}
The life cycle of seaweed Laminaria japonica involves a generation alternation between diploid sporophyte and haploid gametophte. The expression of foreign genes in sporophte has been proved. In this research, the recombinant expression in gametophyte was investigated by particle bombardment with the rt-PA gene encoding the recombinant human tissue-type plasminogen activator (Reteplase), which is a thrombolytic agent for acute myocardial infarction (AMI). Transgenic gametophytes were selected… CONTINUE READING
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