Recombinant congenic strains derived from A/J and C57BL/6J: a tool for genetic dissection of complex traits.

@article{Fortin2001RecombinantCS,
  title={Recombinant congenic strains derived from A/J and C57BL/6J: a tool for genetic dissection of complex traits.},
  author={Anny Fortin and E. Diez and Daniel L. Rochefort and Liette Laroche and Danielle Malo and Guy A Rouleau and Philippe Gros and Emil Skamene},
  journal={Genomics},
  year={2001},
  volume={74 1},
  pages={
          21-35
        }
}
Complex genetic traits can be dissected in mice, using well-defined sets of recombinant inbred strains, congenic strains, and recombinant congenic strains (RCS). We report the creation of a series of 37 independent RCS derived from the commonly used inbred strains of laboratory mouse A/J (A) and C57BL/6J (B6). These RCS were derived by systematic inbreeding of independent pairs of animals from a (F1 x A) x A and a (F1 x B) x B double backcross (N3), to create AcB and BcA strains, respectively… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 65 CITATIONS, ESTIMATED 68% COVERAGE

Characterization of a major colon cancer susceptibility locus (Ccs3) on mouse chromosome 3

  • Oncogene
  • 2010
VIEW 10 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

Positional cloning of a quantitative trait locus contributing to pain sensitivity: possible mediation by Tyrp1.

  • Genes, brain, and behavior
  • 2010
VIEW 6 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Identification of Loci Controlling Restriction of Parasite Growth in Experimental Taenia crassiceps Cysticercosis

  • PLoS neglected tropical diseases
  • 2011
VIEW 9 EXCERPTS
CITES METHODS, BACKGROUND & RESULTS
HIGHLY INFLUENCED

Mapping cis-acting regulatory variation in recombinant congenic strains.

  • Physiological genomics
  • 2006
VIEW 5 EXCERPTS
CITES BACKGROUND, RESULTS & METHODS
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2002
2019

CITATION STATISTICS

  • 14 Highly Influenced Citations