Recombinant canarypoxvirus vaccine carrying the prM/E genes of West Nile virus protects horses against a West Nile virus-mosquito challenge.

@article{Minke2004RecombinantCV,
  title={Recombinant canarypoxvirus vaccine carrying the prM/E genes of West Nile virus protects horses against a West Nile virus-mosquito challenge.},
  author={Jules Maarten Minke and Leonardo Siger and Kemal Karaca and Laura E. Austgen and Paul A. Gordy and Richard Strong Bowen and Randall W. Renshaw and Sheena Loosmore and J C Audonnet and Bob Nordgren},
  journal={Archives of virology. Supplementum},
  year={2004},
  volume={18},
  pages={221-30}
}
An ALVAC (canarypoxvirus)-based recombinant (vCP2017) expressing the prM and E genes derived from a 1999 New York isolate of West Nile virus (WNV) was constructed and assessed for its protective efficacy in horses in two different experiments. In the first trial, a dose titration study was conducted to evaluate both serum neutralising antibody responses to WNV and duration of immunity. In the second trial the onset of protection was determined. Twenty-eight adult horses received two doses of… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
33 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 33 extracted citations

Similar Papers

Loading similar papers…