Recombinant bovine soluble CD14 sensitizes the mammary gland to lipopolysaccharide.

@article{Wang2002RecombinantBS,
  title={Recombinant bovine soluble CD14 sensitizes the mammary gland to lipopolysaccharide.},
  author={Yan Wang and D S Zarlenga and Max J. Paape and Geoffrey E. Dahl},
  journal={Veterinary immunology and immunopathology},
  year={2002},
  volume={86 1-2},
  pages={115-24}
}
Standard therapies including administration of potent antibiotics, aggressive fluid resuscitation and metabolic support have not been successful in relieving symptoms and reducing mortality associated with acute coliform mastitis. It is important to understand the pathophysiological response of the mammary gland to coliform infections when designing preventive or therapeutic regimens for controlling coliform mastitis. Our laboratory has previously shown that macrophages and polymorphonuclear… CONTINUE READING
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