Recombinant antigen-based antibody assays for the diagnosis and surveillance of lymphatic filariasis – a multicenter trial

@article{Lammie2004RecombinantAA,
  title={Recombinant antigen-based antibody assays for the diagnosis and surveillance of lymphatic filariasis – a multicenter trial},
  author={Patrick J. Lammie and Gary J Weil and Rahmah Noordin and Perumal Kaliraj and Cathy Steel and David A. Goodman and Vijaya B Lakshmikanthan and Eric A. Ottesen},
  journal={Filaria Journal},
  year={2004},
  volume={3},
  pages={9 - 9}
}
The development of antifilarial antibody responses is a characteristic feature of infection with filarial parasites. It should be possible to exploit this fact to develop tools to monitor the progress of the global program to eliminate lymphatic filariasis (LF); however, assays based on parasite extracts suffer from a number of limitations, including the paucity of parasite material, the difficulty of assay standardization and problems with assay specificity. In principle, assays based on… CONTINUE READING