Recombinant antibody constructs in cancer therapy.

  title={Recombinant antibody constructs in cancer therapy.},
  author={Peter J. Hudson},
  journal={Current opinion in immunology},
  volume={11 5},
Recombinant antibodies and their fragments now represent over 30% of all biological proteins undergoing clinical trials for diagnosis and therapy. The focus on antibodies as the ideal cancer-targeting reagents recently culminated in approval by the Food and Drugs Administration for the first engineered therapeutic antibodies. In the past year, important advances have been made in the design, selection and production of new types of engineered antibodies. Innovative selection methods have… CONTINUE READING

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