Recombinant antibodies for diagnostics and therapy against pathogens and toxins generated by phage display.

@article{Kuhn2016RecombinantAF,
  title={Recombinant antibodies for diagnostics and therapy against pathogens and toxins generated by phage display.},
  author={Philipp Kuhn and Viola F{\"u}hner and Tobias Unkauf and Gustavo Marçal Schmidt Garcia Moreira and Andr{\'e} Frenzel and Sebastian Miethe and Michael Hust},
  journal={Proteomics. Clinical applications},
  year={2016},
  volume={10 9-10},
  pages={
          922-948
        }
}
Antibodies are valuable molecules for the diagnostic and treatment of diseases caused by pathogens and toxins. Traditionally, these antibodies are generated by hybridoma technology. An alternative to hybridoma technology is the use of antibody phage display to generate recombinant antibodies. This in vitro technology circumvents the limitations of the immune system and allows-in theory-the generation of antibodies against all conceivable molecules. Phage display technology enables obtaining… CONTINUE READING
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