Recombinant antibodies: a natural partner in combinatorial antifungal therapy.

@article{Matthews2004RecombinantAA,
  title={Recombinant antibodies: a natural partner in combinatorial antifungal therapy.},
  author={Ruth Christine Matthews and James Peter Burnie},
  journal={Vaccine},
  year={2004},
  volume={22 7},
  pages={
          865-71
        }
}
Monotherapy, in the form of amphotericin B or one of its liposomal derivatives, is the usual treatment for invasive fungal infections, due to lack of a safe, effective combination of antifungal drugs. Combination therapy is not necessarily beneficial-there may be mutual antagonism or indifference, increased toxicity or interference with concomitant medication. But the benefits of a well-tolerated, synergistic combination would be great-the enhanced efficacy would improve clinical outcome… CONTINUE READING
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