Recombinant anti-human melanoma antibodies are versatile molecules.

@article{Neri1996RecombinantAM,
  title={Recombinant anti-human melanoma antibodies are versatile molecules.},
  author={Dario Neri and Pier Giorgio Natali and Heike Petrul and Patrizia Soldani and Maria Rita Nicotra and R Vola and Alessandro Rivella and Andrew Malcolm Creighton and Paola Neri and Massimo Mariani},
  journal={The Journal of investigative dermatology},
  year={1996},
  volume={107 2},
  pages={
          164-70
        }
}
The low cost, high versatility, and reliable production of bacterially produced recombinant antibody fragments speeds up the development of tumor-targeting agents. High-quality recombinant anti-melanoma antibodies are much sought after in the scientific community. We cloned the murine antibody 225.28S, currently used in radioimmunoimaging of human melanoma lesions, in single-chain Fv configuration (scFv) for soluble expression in bacteria. The recombinant antibody fragment conserved the binding… CONTINUE READING
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