Recombinant adeno-associated virus expressing human papillomavirus type 16 E7 peptide DNA fused with heat shock protein DNA as a potential vaccine for cervical cancer.

Abstract

In this study, we explore a potential vaccine for human papillomavirus (HPV)-induced tumors, using heat shock protein as an adjuvant, a peptide vaccine for safety, and adeno-associated virus (AAV) as a gene delivery vector. The tumor vaccine was devised by constructing a chimeric gene which contained HPV type 16 E7 cytotoxic T-lymphocyte (CTL) epitope DNA… (More)

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Cite this paper

@article{Liu2000RecombinantAV, title={Recombinant adeno-associated virus expressing human papillomavirus type 16 E7 peptide DNA fused with heat shock protein DNA as a potential vaccine for cervical cancer.}, author={D. W. Liu and Y P Tsao and Joseph Kung and Y A Ding and H. K. Sytwu and Xin Xiao and S. L. Chen}, journal={Journal of virology}, year={2000}, volume={74 6}, pages={2888-94} }