Recombinant activated factor VII and the anaesthetist.

@article{Welsby2005RecombinantAF,
  title={Recombinant activated factor VII and the anaesthetist.},
  author={Ian J. Welsby and Dougald M Monroe and Jeffrey Harold Lawson and Megan Hoffmann},
  journal={Anaesthesia},
  year={2005},
  volume={60 12},
  pages={1203-12}
}
Recombinant activated factor VII is a safe and effective for the treatment and prevention of haemorrhage in haemophiliacs with circulating inhibitors to replacement factors, and patients with Glanzmann's thrombasthenia refractory to platelet transfusion. By restoring thrombin generation on the surface of tissue factor bearing cells, such as activated platelets and monocytes, recombinant activated factor VII has the potential to effect haemostasis in the setting of many coagulopathic states… CONTINUE READING

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