Recombinant VAA-I from Viscum album induces apoptotic cell death of hepatocellular carcinoma SMMC7721 cells.

@article{Yang2012RecombinantVF,
  title={Recombinant VAA-I from Viscum album induces apoptotic cell death of hepatocellular carcinoma SMMC7721 cells.},
  author={Xueliang Yang and Shuang Shuang Jiang and Yahui Liu and Ping Zhang and Shuli Xie and Guang-Yi Wang},
  journal={Molecules},
  year={2012},
  volume={17 10},
  pages={11435-46}
}
Researchers have proposed that VAA-I, a specific plant lectin found in Viscum album, has therapeutic effects on cancer and autoimmune diseases. VAA-I has shown some promising treatment results in some types of tumor cell lines, especially SMMC-7721 cells (human hepatocellular carcinoma cells). However, few details are known about the mechanism and process of cell death induced by VAA-I in tumor cells. In this study, the cell morphology results showed that SMMC-7721 cells treated with VAA-I… CONTINUE READING
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