Recombinant Granulocyte-Macrophage Colony-Stimulating Factor (rGM-CSF)

  title={Recombinant Granulocyte-Macrophage Colony-Stimulating Factor (rGM-CSF)},
  author={Susan M. Grant and Rennie C. Heel},
Recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF) is a polypeptide hormone produced through recombinant DNA technologies in glycosylated (yeast or mammalian expression systems) or nonglycosylated (Escherichia coli expression system) form. It is a multilineage haematopoietin which stimulates proliferation and differentiation of bone marrow myeloid progenitors and increases peripheral white blood cell counts when administered systemically. Treatment is generally well… CONTINUE READING
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A double-blind placebo-controlled study with granulocyte-macrophage colony-stimulating factor during chemotherapy for ovarian carcinoma

  • EGE DeVries, B Biesma, PHB Willemse, NH Mulder, AC Stern
  • Cancer Research
  • 1991

A phase I study of GM-CSF cyclophosphamide (CP) and escalating doses of carboplatin (CBDCA) in chemotherapy-naive patients with ovarian cancer

  • J Rusthoven, LLE Eisenhauer, CJ. Mazurka
  • Gynecologic Oncology
  • 1991

Abrogating chemotherapy-induced myelosuppression by GM-CSF: optimizing the schedule. Abstract 1241

  • S Vadhan-Raj, HE Broxmeyer, WN Hittieman, NE Papadopoulos, C Plager
  • Proceedings of the American Society of Clinical…
  • 1991

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