Recombinant Granulocyte-Macrophage Colony-Stimulating Factor (rGM-CSF)

@article{Grant1992RecombinantGC,
  title={Recombinant Granulocyte-Macrophage Colony-Stimulating Factor (rGM-CSF)},
  author={Susan M. Grant and Rennie C. Heel},
  journal={Drugs},
  year={1992},
  volume={43},
  pages={516-560}
}
Recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF) is a polypeptide hormone produced through recombinant DNA technologies in glycosylated (yeast or mammalian expression systems) or nonglycosylated (Escherichia coli expression system) form. It is a multilineage haematopoietin which stimulates proliferation and differentiation of bone marrow myeloid progenitors and increases peripheral white blood cell counts when administered systemically. Treatment is generally well… CONTINUE READING
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