Recombinant Fasciola hepatica fatty acid binding protein suppresses toll-like receptor stimulation in response to multiple bacterial ligands

@inproceedings{RamosBentez2017RecombinantFH,
  title={Recombinant Fasciola hepatica fatty acid binding protein suppresses toll-like receptor stimulation in response to multiple bacterial ligands},
  author={Marcos J. Ramos-Ben{\'i}tez and Caleb Ruiz-Jim{\'e}nez and Vasti Aguayo and Ana M. Espino},
  booktitle={Scientific Reports},
  year={2017}
}
Recently, we reported that a native Fasciola hepatica fatty acid binding protein (FABP) termed Fh12 is a powerful anti-inflammatory protein capable of suppressing the LPS-induced expression of inflammatory markers in vivo and in vitro. Because the purification of a protein in native form is, in many situations not cost-beneficial and unsuitable for industrial grade scale-up, this study accomplished the task of optimizing the expression and purification of a recombinant form of FABP (Fh15… CONTINUE READING

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Temperature excursion management: A novel approach of quality system in pharmaceutical industry.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society • 2017

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