Recombinant BCG therapy suppresses melanoma tumor growth

  title={Recombinant BCG therapy suppresses melanoma tumor growth},
  author={Dr. Rosemary B. Duda and Hua Yang and Danielle D. Dooley and Graziella M Abu-Jawdeh},
  journal={Annals of Surgical Oncology},
Background: Melanoma is the fastest rising cancer in the United States. Bacillus Calmette-Guerin (BCG) has been genetically engineered to actively express and secrete the cytokine interleukin-2 (IL-2). Both BCG and IL-2 have known potent antitumor and immunomodulatory properties. Methods: This recombinant BCG (rBCG 3A) has been tested as an intratumoral… CONTINUE READING