Recognizing the fold of a protein structure

@article{Harrison2003RecognizingTF,
  title={Recognizing the fold of a protein structure},
  author={Andrew P. Harrison and Frances M. G. Pearl and Ian Sillitoe and Tim Slidel and Richard Mott and Janet M. Thornton and Christine A. Orengo},
  journal={Bioinformatics},
  year={2003},
  volume={19 14},
  pages={1748-59}
}
This paper reports a graph-theoretic program, GRATH, that rapidly, and accurately, matches a novel structure against a library of domain structures to find the most similar ones. GRATH generates distributions of scores by comparing the novel domain against the different types of folds that have been classified previously in the CATH database of structural domains. GRATH uses a measure of similarity that details the geometric information, number of secondary structures and number of residues… CONTINUE READING

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