Recognition of two distinct major antigens by bullous pemphigoid sera.

@article{Cook1990RecognitionOT,
  title={Recognition of two distinct major antigens by bullous pemphigoid sera.},
  author={A. L. Cook and T. H. P. Hanahoe and Richard B Mallett and R J Pye},
  journal={The British journal of dermatology},
  year={1990},
  volume={122 4},
  pages={
          435-44
        }
}
Sera from 17 patients with bullous pemphigoid identified a range of polypeptides of relative molecular mass (Mr) 240,000, 230,000, 190,000, 180,000, 120,000 and 100,000 from extracts of SCaBER cells, cultured human keratinocytes or human epidermis, using an immunoblotting technique. The pattern of polypeptides was characteristic for the patient serum and individual sera identified similar polypeptides from all three substrates. All 17 sera recognized major polypeptides of either Mr 230,000 (11… CONTINUE READING

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