Recognition of the small regulatory RNA RydC by the bacterial Hfq protein

@inproceedings{Dimastrogiovanni2014RecognitionOT,
  title={Recognition of the small regulatory RNA RydC by the bacterial Hfq protein},
  author={Daniela Dimastrogiovanni and Kathrin Sophie Fr{\"o}hlich and Katarzyna J. Bandyra and Heather A Bruce and Susann Hohensee and J{\"o}rg Vogel and Ben F Luisi},
  booktitle={eLife},
  year={2014}
}
Bacterial small RNAs (sRNAs) are key elements of regulatory networks that modulate gene expression. The sRNA RydC of Salmonella sp. and Escherichia coli is an example of this class of riboregulators. Like many other sRNAs, RydC bears a 'seed' region that recognises specific transcripts through base-pairing, and its activities are facilitated by the RNA chaperone Hfq. The crystal structure of RydC in complex with E. coli Hfq at a 3.48 Å resolution illuminates how the protein interacts with and… CONTINUE READING
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