Recognition of mucin by the adhesin-flagellar system of Pseudomonas aeruginosa.

  title={Recognition of mucin by the adhesin-flagellar system of Pseudomonas aeruginosa.},
  author={Reuben Ramphal and Shiwani K. Arora and B W Ritchings},
  journal={American journal of respiratory and critical care medicine},
  volume={154 4 Pt 2},
Pseudomonas aeruginosa colonizes the mucus of patients with chronic lung diseases by a specific mechanism involving an adhesin-receptor system. Several adhesins have been implicated in the adhesion of P. aeruginosa to cells, but the identity of the principal adhesin(s) involved in adhesion to mucin is unknown. Mutagenesis studies have indicated that P. aeruginosa adhesion is under the control of the rpoN gene, which also regulates pilin synthesis, flagellum formation, and other functions… CONTINUE READING

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