Recognition of immunoglobulins by Fcgamma receptors.

  title={Recognition of immunoglobulins by Fcgamma receptors.},
  author={Sergei Radaev and Peter D. Sun},
  journal={Molecular immunology},
  volume={38 14},
Fc receptors mediate antibody dependent inflammatory response and cytotoxicity as well as certain autoimmune dysfunctions. Fcgamma receptors interact with IgG antibodies by binding the Fc portion of the antibody in asymmetric fashion creating a 1:1 receptor-ligand stoichiometry. Regions of the C-terminal domain of Fc receptors including the BC, C'E, FG… CONTINUE READING