Recognition of desmoglein 3 by autoreactive T cells in pemphigus vulgaris patients and normals.

@article{Hertl1998RecognitionOD,
  title={Recognition of desmoglein 3 by autoreactive T cells in pemphigus vulgaris patients and normals.},
  author={Michael Hertl and Masayuki Amagai and Hari Sundaram and Jill Stanley and Ken J Ishii and Stephen I. Katz},
  journal={The Journal of investigative dermatology},
  year={1998},
  volume={110 1},
  pages={62-6}
}
Pemphigus vulgaris (PV) is an autoimmune blistering disease of the skin and is caused by autoantibodies against desmoglein 3 (Dsg3) on epidermal keratinocytes. Because the production of autoantibodies is presumably T cell dependent, Dsg3-specific T cell reactivity was investigated in 14 PV patients and 12 healthy donors. Peripheral blood mononuclear cells from seven PV patients with active disease showed a primary in vitro response to a recombinant protein containing the extracellular portion… CONTINUE READING

From This Paper

Topics from this paper.
30 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 30 extracted citations

Similar Papers

Loading similar papers…