Recognition of core binding sites by bacteriophage integrases.

  title={Recognition of core binding sites by bacteriophage integrases.},
  author={L{\'a}szl{\'o} Dorgai and Stephen B. Sloan and Robert A. Weisberg},
  journal={Journal of molecular biology},
  volume={277 5},
Bacteriophage integrases promote recombination between DNA molecules that carry attachment sites. They are members of a large and widely distributed family of site-specific recombinases with diverse biological roles. The integrases of phages lambda and HK022 are closely related members of this family, but neither protein efficiently recombines the attachment sites of the other phage. The nucleotides responsible for this specificity difference are located close to the points of recombinational… CONTINUE READING
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