Recognition of a dopamine replacement therapy dependence syndrome in Parkinson's disease: a pilot study.

@article{Bearn2004RecognitionOA,
  title={Recognition of a dopamine replacement therapy dependence syndrome in Parkinson's disease: a pilot study.},
  author={Jennifer Bearn and Andrew Stephen Evans and Michael Kelleher and Kirsten Turner and Andrew Lees},
  journal={Drug and alcohol dependence},
  year={2004},
  volume={76 3},
  pages={305-10}
}
Patients with Parkinson's disease may use Dopamine Replacement Therapy (DRT) in excess of therapeutic need. We investigate whether a group of 10 patients with Parkinson's disease, provisionally diagnosed with "Hedonistic Homeostatic Dysregulation" because of their excessive use of DRT, met established operational psychiatric criteria for substance dependence, compared with 10 patients with Parkinson's disease compliant with prescribed DRT. Using a semi-structured questionnaire designed to… CONTINUE READING