Recognition of Treponema pallidum antigens by IgM and IgG antibodies in congenitally infected newborns and their mothers.

@article{Dobson1988RecognitionOT,
  title={Recognition of Treponema pallidum antigens by IgM and IgG antibodies in congenitally infected newborns and their mothers.},
  author={Simon R M Dobson and Larry H Taber and Robert E. Baughn},
  journal={The Journal of infectious diseases},
  year={1988},
  volume={157 5},
  pages={903-10}
}
Immunoblotting techniques were used to examine the proteins of Treponema pallidum recognized by IgM and IgG antibodies in sera from infants with congenital syphilis and their mothers. Infected infants' serum IgM reactivity to treponemal antigens differed from that of control infants born to normal, serofast, and biologic false-positive mothers. Each of the infected infants' sera exhibited IgM reactions to the 47- and 37-kilodalton (kDa) proteins of T. pallidum. Although rheumatoid factor was… CONTINUE READING

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