Recognition of Microbial Glycolipids by Natural Killer T Cells

@inproceedings{Zajonc2015RecognitionOM,
  title={Recognition of Microbial Glycolipids by Natural Killer T Cells},
  author={Dirk M. Zajonc and Enrico Girardi},
  booktitle={Front. Immunol.},
  year={2015}
}
T cells can recognize microbial antigens when presented by dedicated antigen-presenting molecules. While peptides are presented by classical members of the major histocompatibility complex (MHC) family (MHC I and II), lipids, glycolipids, and lipopeptides can be presented by the non-classical MHC member, CD1. The best studied subset of lipid-reactive T cells are type I natural killer T (iNKT) cells that recognize a variety of different antigens when presented by the non-classical MHCI homolog… CONTINUE READING

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