Recognition of Binding Patterns Common to a Set of Protein Structures

@inproceedings{Shatsky2005RecognitionOB,
  title={Recognition of Binding Patterns Common to a Set of Protein Structures},
  author={Maxim Shatsky and Alexandra Shulman-Peleg and Ruth Nussinov and Haim J. Wolfson},
  booktitle={RECOMB},
  year={2005}
}
We present a novel computational method, MultiBind, for recognition of binding patterns common to a set of protein structures. It is the first method which performs a multiple alignment between protein binding sites in the absence of overall sequence, fold or binding partner similarity. MultiBind recognizes common spatial arrangements of physico-chemical properties in the binding sites. These should be important for recognition of function, prediction of binding and drug design. We discuss the… CONTINUE READING
Highly Cited
This paper has 45 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

Geometry-based Methods for Protein Function Prediction

Kevin R. Mac
2010
View 8 Excerpts
Highly Influenced

Composite motifs integrating multiple protein structures increase sensitivity for function prediction.

Computational systems bioinformatics. Computational Systems Bioinformatics Conference • 2007
View 6 Excerpts
Highly Influenced

Superposition of protein structures using electrostatic isopotentials

2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) • 2015

Aligning ligand binding cavities by optimizing superposed volume

2012 IEEE International Conference on Bioinformatics and Biomedicine • 2012

Improving accuracy in binding site comparison with homology modeling

2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops • 2012
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 34 references

On the approximation of largest common subtrees and largest common point sets

T. Akutsu, M. M. Halldorson
Theoretical Computer Science 233 • 2000
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…