Recognition and maturation of effector RNAs in a CRISPR interference pathway

@article{Gesner2011RecognitionAM,
  title={Recognition and maturation of effector RNAs in a CRISPR interference pathway},
  author={Emily M. Gesner and Matthew J. Schellenberg and Erin L. Garside and Mark M George and Andrew M. MacMillan},
  journal={Nature Structural &Molecular Biology},
  year={2011},
  volume={18},
  pages={688-692}
}
  • Emily M. Gesner, Matthew J. Schellenberg, +2 authors Andrew M. MacMillan
  • Published 2011
  • Biology, Medicine
  • Nature Structural &Molecular Biology
  • In bacteria and archaea, small RNAs derived from clustered, regularly interspaced, short palindromic repeat (CRISPR) loci are involved in an adaptable and heritable gene-silencing pathway. Resistance to phage infection is conferred by the incorporation of short invading DNA sequences into the genome as CRISPR spacer elements separated by short repeat sequences. Processing of long primary transcripts (pre-crRNAs) containing these repeats by an RNA endonuclease generates the mature effector RNAs… CONTINUE READING

    Figures, Tables, and Topics from this paper.

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 152 CITATIONS, ESTIMATED 62% COVERAGE

    Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases

    VIEW 4 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    FILTER CITATIONS BY YEAR

    2011
    2019

    CITATION STATISTICS

    • 11 Highly Influenced Citations

    • Averaged 7 Citations per year from 2018 through 2020

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 34 REFERENCES