Recognition and management of withdrawal delirium (delirium tremens).

  title={Recognition and management of withdrawal delirium (delirium tremens).},
  author={Marc A. Schuckit},
  journal={The New England journal of medicine},
  volume={371 22},
  • M. Schuckit
  • Published 26 November 2014
  • Medicine, Psychology
  • The New England journal of medicine
Alcohol withdrawal syndromes are underdiagnosed and understudied. Prevention and treatment involve supportive care and administration of benzodiazepines. 

Haloperidol for delirium tremens as an adjunct treatment to benzodiazepines: experience of a hospital alcohol team

Haloperidol is recommended as an adjunct to benzodiazepines in these cases of refractory delirium tremens that does not respond to Benzodiazepine.

Dexmedetomidine as adjunctive therapy for the treatment of alcohol withdrawal syndrome

ABSTRACTObjective:The purpose of this review is to evaluate the effectiveness and safety of dexmedetomidine as adjunctive therapy to the standard of care (benzodiazepines) compared to either the

Alcohol withdrawal.

This is considered a guidance document only and clinical judgment is necessary to assess a patient’s degree of alcohol tolerance in the context of their symptoms, signs, and blood alcohol concentration.

Assessing a patient with alcohol intoxication

How to examine, assess, clerk, and safely discharge patients presenting with alcohol intoxication

Alcohol withdrawal syndrome: mechanisms, manifestations, and management

The purpose of this review is to increase the awareness of the early clinical manifestations of AWS and the appropriate identification and management of this important condition in a neurological setting.

The ASAM Clinical Practice Guideline on Alcohol Withdrawal Management: Erratum.

Brief report only Conference abstracts

Common Postoperative and Inpatient Issues

This chapter reviews the diagnosis and management of common issues in the care of postoperative and admitted patients, including oliguria, tachycardia, sinus bradycardia, asymptomatic hypertension,

Chlordiazepoxide-induced delirium in a patient undergoing alcohol withdrawal: a case report

Worsening of delirium appears to be related to the specific use of chlordiazepoxide, but the mechanism of this effect is not clear.

Outcomes After Implementation of a Benzodiazepine-Sparing Alcohol Withdrawal Order Set in an Integrated Health Care System

This quality improvement study investigates the association of a benzodiazepine-sparing order set at an integrated health care system with medication use and health care outcomes among patients with



Symptom‐Driven Lorazepam Protocol for Treatment of Severe Alcohol Withdrawal Delirium in the Intensive Care Unit

To compare outcomes of treating alcohol withdrawal delirium with a symptom‐driven benzodiazepine protocol versus nonprotocol benzodiazine infusions in the intensive care unit (ICU) is compared.

Management of drug and alcohol withdrawal.

This review summarizes the current approaches to the management of withdrawal in patients addicted to sedatives such as alcohol or benzodiazepines, opioids, or stimulants such as amphetamines or

The role of carbamazepine and oxcarbazepine in alcohol withdrawal syndrome

Objective:  The goal of this review is to evaluate the efficacy and safety of carbamazepine and oxcarbazepine in treatment of alcohol withdrawal syndrome (AWS) and determine the role in therapy of

Massive doses of midazolam infusion for delirium tremens without respiratory depression.

After undergoing replantation and revascularization surgery for a complex hand injury, a 25-yr-old male developed florid delirium tremens. Over a 5-day period, he received 2850 mg of midazolam as a

Alcohol withdrawal delirium - diagnosis, course and treatment.

When not early recognized and treated adequately, delirium tremens may result in death due to malignant arrhythmia, respiratory arrest, sepsis, severe electrolyte disturbance or prolonged seizures and subsequent trauma.

Management of alcohol withdrawal delirium. An evidence-based practice guideline.

Control of agitation should be achieved using parenteral rapid-acting sedative-hypnotic agents that are cross-tolerant with alcohol, andequate doses should be used to maintain light somnolence for the duration of delirium.

Use of propofol infusion in alcohol withdrawal-induced refractory delirium tremens.

This study suggests that treatment with propofol is viable in refractory delirium tremens, and establishing indication, dose, duration, and long-term effects of prop ofol treatment of deliria tremens requires further investigation.

The histories of withdrawal convulsions and delirium tremens in 1648 alcohol dependent subjects.

Hierarchical logistic regression analysis revealed that the most powerful differences between those with histories of more and less severe withdrawals related to the maximum number of drinks per day and the total number of withdrawal episodes.

Risk factors for delirium tremens: a retrospective chart review.

A retrospective chart review was performed within an inpatient VA hospital setting in an attempt to identify risk factors for delirium tremens, and there were differences in reason for admission and relapse rate upon follow-up between the groups.

Thrombocytopenia in early alcohol withdrawal is associated with development of delirium tremens or seizures.

Thrombocytopenia is more frequent in patients who develop severe AWS (DT or seizures) and must be interpreted with caution due to the small number of patients who developed AWS, so further studies replicating the present finding are needed.