A system was developed for automatic ECG analysis, which involved a screening program and algorithms for syndrome ECG diagnosis. The principles for synthesizing algorithms for syndrome diagnosis are exemplified by the decision rule of identifying a ECG syndrome of atrial hypertrophy. The specificity of the proposed algorithm was more than 90%. Severe left and right atrial and moderate right atrial hypertrophies were well recognized. The findings suggest that the developed rules might be useful in the system of automatic ECG analysis.