Reciprocal stimulation of gammadelta T cells and dendritic cells during the anti-mycobacterial immune response.

Abstract

Gammadelta T cells and dendritic cells (DC) are two distinct cell types of innate immunity that participate in early phases of immune response against Mycobacterium tuberculosis infection. Here we show that a close functional relationship exists between these cell populations. Using an in vitro coculture system, Vgamma1 T cells from Tcrb(-/- )mice were… (More)

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