Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation.

Abstract

Mice deficient in the Msx2 gene manifest defects in skull ossification and a marked reduction in bone formation associated with decreases in osteoblast numbers, thus suggesting that Msx2 is involved in bone formation. However, the precise role of Msx2 during osteoblast differentiation is not fully understood. In the present study, we investigated the role… (More)

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@article{Ichida2004ReciprocalRO, title={Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation.}, author={Fumitaka Ichida and Riko Nishimura and Kenji Hata and Takuma Matsubara and Fumiyo Ikeda and Kunihiro Hisada and Hirofumi Yatani and Xu Cao and Toshihisa Komori and Akira Yamaguchi and Toshiyuki Yoneda}, journal={The Journal of biological chemistry}, year={2004}, volume={279 32}, pages={34015-22} }