Reciprocal interactions of insulin and insulin-like growth factor I in receptor-mediated transport across the blood-brain barrier.

Abstract

Although the blood-brain barrier limits free passage of peptides and proteins from the peripheral circulation to the central nervous system, specific transport systems for insulin and IGF-I have been identified. To further determine whether insulin and IGF-I share the same transport system, and if not, whether the two transport systems interact with each… (More)

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@article{Yu2006ReciprocalIO, title={Reciprocal interactions of insulin and insulin-like growth factor I in receptor-mediated transport across the blood-brain barrier.}, author={Yongmei Yu and Abba J. Kastin and Weihong Pan}, journal={Endocrinology}, year={2006}, volume={147 6}, pages={2611-5} }