Reciprocal immune benefit based on complementary production of antibiotics by the leech Hirudo verbana and its gut symbiont Aeromonas veronii

@inproceedings{Tasiemski2015ReciprocalIB,
  title={Reciprocal immune benefit based on complementary production of antibiotics by the leech Hirudo verbana and its gut symbiont Aeromonas veronii},
  author={Aur{\'e}lie Tasiemski and François Massol and Virginie Cuvillier-Hot and C{\'e}line Boidin-Wichlacz and Emmanuel Roger and Franck Rodet and Isabelle Fournier and Fr{\'e}d{\'e}ric Thomas and Michel Salzet},
  booktitle={Scientific reports},
  year={2015}
}
The medicinal leech has established a long-term mutualistic association with Aeromonas veronii, a versatile bacterium which can also display free-living waterborne and fish- or human-pathogenic lifestyles. Here, we investigated the role of antibiotics in the dynamics of interaction between the leech and its gut symbiont Aeromonas. By combining biochemical and molecular approaches, we isolated and identified for the first time the antimicrobial peptides (AMPs) produced by the leech digestive… CONTINUE READING

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