Reciprocal cross-talk between Prostaglandin E2 and bone in prostate cancer: a current review

@inproceedings{Francesco2011ReciprocalCB,
  title={Reciprocal cross-talk between Prostaglandin E2 and bone in prostate cancer: a current review},
  author={Simona Di Francesco and Pietro Castellan and Rossella Manco and Raffaele Lanfranco Tenaglia},
  booktitle={Central European journal of urology},
  year={2011}
}
In this review we analyzed the role of PGE2 as a possible regulator of bone metabolism and bone metastases in prostate cancer. Published studies were identified by searching computerized bibliographic systems from January 1(st), 2000 to July 1(st), 2011. PGE2 represents a key factor in the modulation of bone metabolism and bone metastatic disease in prostate cancer interacting with bone regulatory signals including the RANK/RANKL/OPG system and Wnt pathways. A high concentration of PGE2 exerts… CONTINUE READING