Reciprocal changes in prolactin and growth hormone secretion in vitro after in vivo estrogen treatment.

@article{Horvth1994ReciprocalCI,
  title={Reciprocal changes in prolactin and growth hormone secretion in vitro after in vivo estrogen treatment.},
  author={Judit E Horv{\'a}th and Andrew V Schally},
  journal={Acta biologica Hungarica},
  year={1994},
  volume={45 2-4},
  pages={249-62}
}
Female rats were treated in vivo with estrogen for three weeks. The pituitaries were then removed and their responses to somatostatin, dopamine, TRH, hGHRH(1-44)NH2, or their combination were examined in a superfused pituitary cell system. Somatostatin did not decrease basal prolactin secretion in the control cells, but it caused a dose-dependent decrease in prolactin release from the estrogen pretreated cells. Estrogen pretreatment did not alter the sensitivity of pituitary cells to dopamine… CONTINUE READING