Recipient NOD2/CARD15 status affects cellular infiltrates in human intestinal graft-versus-host disease.

@article{Landfried2010RecipientNS,
  title={Recipient NOD2/CARD15 status affects cellular infiltrates in human intestinal graft-versus-host disease.},
  author={Karin Landfried and F Bataille and Gerhard Rogler and Julia Brenmoehl and Katrin Kosovac and D Wolff and Inken Hilgendorf and Jamie Hahn and Matthias Edinger and Petra Hoffmann and Florian Obermeier and Juergen Schoelmerich and Reinhard Andreesen and Ernst Holler},
  journal={Clinical and experimental immunology},
  year={2010},
  volume={159 1},
  pages={87-92}
}
Nucleotide-binding oligomerization domain 2/caspase recruitment domain 15 (NOD2/CARD15) polymorphisms have been identified as risk factors of both Crohn's disease and graft-versus-host disease (GVHD) following allogeneic stem cell transplantation. However, the role of these receptors of innate immunity in the pathophysiology of gastrointestinal GVHD is still poorly defined. Immunohistological features of intestinal GVHD were analysed in gastrointestinal biopsies from 58 patients obtained at the… CONTINUE READING
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