Rechallenging Clozapine After Neuroleptic Malignant Syndrome

@article{Anbalagan2014RechallengingCA,
  title={Rechallenging Clozapine After Neuroleptic Malignant Syndrome},
  author={Emaya Anbalagan and Muaid Ithman and John Lauriello},
  journal={Psychiatric Quarterly},
  year={2014},
  volume={85},
  pages={345-348}
}
Neuroleptic malignant syndrome (NMS) is a potentially fatal manifestation of antipsychotic use associated with symptoms that include mental status changes, muscle rigidity, fever and autonomic dysfunction. An occurrence of NMS with clozapine has been reported in the past but there are very few reports of successfully rechallenging the drug in individuals who have developed the syndrome. This case report discusses one of the few instances in literature where clozapine has been re-administered… CONTINUE READING