Recessive oligodontia linked to a homozygous loss-of-function mutation in the SMOC2 gene.

Abstract

OBJECTIVE Recently, several genes have been reported with mutations or variants that underlie a number of syndromic and non-syndromic forms of oligodontia including MSX1, PAX9, AXIN2, EDA and WNT10A. This study aimed to identify the causal mutations in a consanguineous Pakistan family with oligodontia and microdontia. DESIGN Exome sequencing was performed… (More)
DOI: 10.1016/j.archoralbio.2012.12.008

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