Receptors in the Ventral Tegmental Area Mediating Nicotine-Induced Dopamine Release in the Nucleus Accumbens

@article{Szirki2004ReceptorsIT,
  title={Receptors in the Ventral Tegmental Area Mediating Nicotine-Induced Dopamine Release in the Nucleus Accumbens},
  author={Istv{\'a}n Szir{\'a}ki and Henry W. Sershen and Audrey Hashim and Abel Lajtha},
  journal={Neurochemical Research},
  year={2004},
  volume={27},
  pages={253-261}
}
Nicotine or cocaine, when administered intravenously, induces an increase of extracellular dopamine in the nucleus accumbens. The nicotine-mediated increase was shown to occur at least in part through increase of the activity of dopamine neurons in the ventral tegmental area. As part of our continuing studies of the mechanisms of nicotine effects in the brain, in particular, effects on reward and cognitive mechanisms, in the present study we examined the role of various receptors in the ventral… Expand
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ON THE ROLE OF NMDA RECEPTOR SUBUNITS IN THE ACUTE AND CHRONIC EFFECTS OF NICOTINE
Nicotine is considered the main dependence-producing constituent in tobacco products. In analogy with other drugs of abuse, nicotine enhances dopamine (DA) neurotransmission within theExpand
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