Receptors for human IgG subclasses on human alveolar macrophages.

  title={Receptors for human IgG subclasses on human alveolar macrophages.},
  author={G P Naegel and K. Randall Young and Herbert Y. Reynolds},
  journal={The American review of respiratory disease},
  volume={129 3},
The biology of individual heavy chain subclasses of human IgG (IgG1-4) in lung host defenses has become important now that specific deficiencies of certain subclasses (IgG2 and IgG4) can be associated with chronic sinopulmonary infections and that IgG4 can be increased in forms of hypersensitivity lung disease. Because IgG is an important opsonic antibody that promotes attachment of bacteria or particles to phagocytes, the relative binding of IgG subclasses to membrane receptors on human… CONTINUE READING


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