Receptors for epidermal growth factor and steroid hormones in human breast cancer.

@article{Battaglia1988ReceptorsFE,
  title={Receptors for epidermal growth factor and steroid hormones in human breast cancer.},
  author={Francesco Antonino Battaglia and Giovanni Polizzi and Giovanni Scambia and Simone Rossi and Pierluigi Benedetti Panici and Stefano Iacobelli and Francesco Crucitti and Salvatore Mancuso},
  journal={Oncology},
  year={1988},
  volume={45 6},
  pages={424-7}
}
Epidermal growth factor (EGF) seems to play an important role in regulating the proliferation of human breast cancer. Fifty-five primary breast tumors and 7 lymph node metastases were simultaneously assayed for the presence of EGF receptors (EGFR), estrogen receptors (ER), and progesterone receptors (PR). Overall, 42% (23/55) of the tumors were EGFR positive. EGFR were more frequently present in ER- and PR-negative than in ER- and PR-positive tumors. In particular, a negative correlation… CONTINUE READING
6 Citations
0 References
Similar Papers