Receptors for epidermal growth factor and other polypeptide mitogens.

@article{Carpenter1987ReceptorsFE,
  title={Receptors for epidermal growth factor and other polypeptide mitogens.},
  author={Graham Carpenter},
  journal={Annual review of biochemistry},
  year={1987},
  volume={56},
  pages={
          881-914
        }
}
  • G. Carpenter
  • Published 1987
  • Biology, Medicine
  • Annual review of biochemistry

Topics from this paper

Epidermal growth factor receptor-protein kinase interactions in hepatic membranes of rainbow trout (Oncorhynchus mykiss)
TLDR
The hypothesis that trout have an EGF-like receptor that has binding and biological activities similar to that observed in mammalian species is supported. Expand
Expression of ras oncogene p21 protein in normal and neoplastic laryngeal tissues: correlation with histopathological features and epidermal growth factor receptors.
TLDR
It is suggested that overexpression of p21 protein is associated with a malignant phenotype in laryngeal cancer and further studies should be undertaken to evaluate whether the assessment of p 21 protein expression may have clinical significance in l throat cancer. Expand
Synthesis, characterisation and biological activity of silicon nanoparticles functionalised by anticancer compounds
Abstract Silicon Nanoparticles (SiNPs) are non-toxic materials particularly suitable for various biomedical applications. They exhibit unique optical properties for use in bioimaging and diagnosticExpand
Tyrosine phosphorylation of p145met mediated by EGFR and Src is required for serum-independent survival of human bladder carcinoma cells
TLDR
The results suggest that the serum-independent growth of 5637 cells involves the transmembrane signaling cascade via EGFR ligand(s) (but not HGF), EGFR, Src and p145met. Expand
The role of epidermal growth factor and its receptors in mammalian CNS.
TLDR
This review highlights some of the major recent findings pertinent to the EGF and ErbB family with special references to elucidating their roles in the regulation of neurogenesis, signal transduction and trafficking and degradation. Expand
Expression of epidermal growth factor and platelet-derived growth factor receptors during cervical carcinogenesis
TLDR
A role for EGFR and PDGFR during the early stages of cervical carcinogensis is suggested, and the facility of organotypic cultures to study the role of these growth factors in the development of cervical cancer is demonstrated. Expand
Mammary Tumorigenesis and Malignant Progression
Growth Factors in Reproduction
TLDR
Information of interest to both scientists and clinicians is outlined, with respect to cellular actions of growth factors, their unique regulatory roles in developing and differentiated cell systems, and their involvement in the neoplastic transformation of steroid target cells. Expand
Vascular Endothelial Cell Growth Factor A Acts via Platelet-Derived Growth Factor Receptor α To Promote Viability of Cells Enduring Hypoxia
TLDR
It is reported here that both VEGF receptor 2 (VEGFR2)-positive and -negative cells depended on V EGF to endure hypoxia and a plausible mechanistic explanation of this phenomenon is proposed. Expand
...
1
2
3
4
5
...