Receptors for complement and immunoglobulin on human leukemic cells and human lymphoblastoid cell lines.

@article{Shevach1972ReceptorsFC,
  title={Receptors for complement and immunoglobulin on human leukemic cells and human lymphoblastoid cell lines.},
  author={Ethan M Shevach and R Herberman and Mike Frank and Ira Green},
  journal={The Journal of clinical investigation},
  year={1972},
  volume={51 8},
  pages={1933-8}
}
The bone marrow-derived (B) lymphocyte can be identified by the presence of easily detectable surface immunoglobulin and a receptor for antigen-antibody-complement complexes (EAC'). Monocytes and macrophages also bear a receptor for EAC' and in addition possess a receptor for red cell-IgG complexes (EA). Thymus-derived (T) lymphocytes bear neither of these receptors. The cells of 15 patients with leukemia and 19 human lymphoblastoid cell lines were examined for the presence of the EAC' and EA… CONTINUE READING