Receptors for cholecystokinin and gastrin peptides display specific binding properties and are structurally different in guinea-pig and dog pancreas.

@article{Fourmy1987ReceptorsFC,
  title={Receptors for cholecystokinin and gastrin peptides display specific binding properties and are structurally different in guinea-pig and dog pancreas.},
  author={Daniel Fourmy and A Zahidi and Richard Fabre and M Guidet and Lucien Pradayrol and Andr{\'e} Ribet},
  journal={European journal of biochemistry},
  year={1987},
  volume={165 3},
  pages={683-92}
}
In the light of the strong potency of gastrin-related peptides on pancreatic exocrine secretion in dog, we analyzed the binding properties of peptides related to cholecystokinin (CCK) and gastrin on dog pancreatic acini compared to guinea-pig acini. Moreover, we determined apparent molecular masses of photoaffinity labelled CCK/gastrin receptors in the two models. Using the CCK radioligand, receptor selectivity towards CCK/gastrin agonists and antagonists was found to be lower in dog acini than… CONTINUE READING

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Cholecystokinin Antagonists in Gastroenterology

Springer Berlin Heidelberg • 1991
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Characterization of gastrin binding to colonic mucosal membranes of guinea pigs

Molecular and Cellular Biochemistry • 1992
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Role of cholecystokinin in the intestinal phase of pancreatic circulation in dogs.

American journal of physiology. Gastrointestinal and liver physiology • 2001
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