Receptor usage and differential downregulation of CD46 by measles virus wild-type and vaccine strains.

@article{SchneiderSchaulies1995ReceptorUA,
  title={Receptor usage and differential downregulation of CD46 by measles virus wild-type and vaccine strains.},
  author={J{\"u}rgen Schneider-Schaulies and J J Schnorr and Ute Brinckmann and L. M. Dunster and Knut Baczko and Uwe Gerd Liebert and S Schneider-Schaulies and Volker ter Meulen},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1995},
  volume={92 9},
  pages={
          3943-7
        }
}
Recently, two cell surface molecules, CD46 and moesin, have been found to be functionally associated with measles virus (MV) infectivity of cells. We investigated the receptor usage of MV wild-type, subacute sclerosing panencephalitis, and vaccine strains and their effect on the down-regulation of CD46 after infection. We found that the infection of human cell lines with all 19 MV strains tested was inhibitable with antibodies against CD46. In contrast, not all strains of MV led to the… CONTINUE READING

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