Receptor tyrosine kinase inhibitors: molecularly targeted drugs for veterinary cancer therapy.


Tyrosine kinases (TKs) are key mediators of signalling pathways in cells. Located at the surface of the cell, within the cytoplasm or in the nucleous, TKs have been showed to be involved in regulation of normal cellular processes and also play an important role in the development, progression and spread of several types of cancer. Seventy percent of TK's… (More)
DOI: 10.1111/j.1476-5829.2012.00342.x


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