Receptor subtypes Y1 and Y5 mediate neuropeptide Y induced feeding in the guinea-pig.

@article{Lecklin2002ReceptorSY,
  title={Receptor subtypes Y1 and Y5 mediate neuropeptide Y induced feeding in the guinea-pig.},
  author={Anne Lecklin and Ingrid Lundell and Leena Paananen and Jarl E. S. Wikberg and Pekka T. M{\"a}nnist{\"o} and Dan Larhammar},
  journal={British journal of pharmacology},
  year={2002},
  volume={135 8},
  pages={2029-37}
}
1. Neuropeptide Y (NPY) is one of the most potent stimulants of food intake. It has been debated which receptor subtype mediates this response. Initially Y(1) was proposed, but later Y(5) was announced as a 'feeding' receptor in rats and mice. Very little is known regarding other mammals. The present study attempts to characterize the role of NPY in feeding behaviour in the distantly related guinea-pig. When infused intracerebroventricularly, NPY dose-dependently increased food intake. 2. PYY… CONTINUE READING