Receptor stimulated accumulation of phosphatidylinositol (3,4,5)-trisphosphate by G-protein mediated pathways in human myeloid derived cells.

Abstract

Phosphoinositide 30H-kinase (PI3K) activities are thought to be critical regulatory enzymes in a new intracellular signalling pathway, the activation of which results in the rapid accumulation of a putative signalling molecule, phosphatidylinositol (3,4,5)-trisphosphate [PtdIns(3,4,5) P3]. To date, activation of PI3K has always correlated with its… (More)

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@article{Stephens1993ReceptorSA, title={Receptor stimulated accumulation of phosphatidylinositol (3,4,5)-trisphosphate by G-protein mediated pathways in human myeloid derived cells.}, author={Len R. Stephens and Alicia Eguinoa and S J Corey and Tom R. Jackson and Phillip T. Hawkins}, journal={The EMBO journal}, year={1993}, volume={12 6}, pages={2265-73} }